GALC (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GALC partial ORF ( NP_000144, 596 a.a. - 669 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AGWIIYALGRVEVTAKKWYTLTLTIKGHFASGMLNDKSLWTDIPVNFPKNGWAAIGTHSFEFAQFDNFLVEATR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.88
Interspecies Antigen Sequence
Mouse (68)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GALC
Entrez GeneID
2581GeneBank Accession#
NM_000153Protein Accession#
NP_000144Gene Name
GALC
Gene Alias
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Gene Description
galactosylceramidase
Gene Ontology
HyperlinkGene Summary
This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
GALCERase|OTTHUMP00000027906|galactocerebrosidase|galactocerebroside beta-galactosidase|galactosylceramide beta-galactosidase|galactosylceraminidase
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Interactome
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Pathway
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