GABRB3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human GABRB3 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GABRB3
Entrez GeneID
2562GeneBank Accession#
NM_021912.3Protein Accession#
NP_068712.1Gene Name
GABRB3
Gene Alias
ECA5, MGC9051
Gene Description
gamma-aminobutyric acid (GABA) A receptor, beta 3
Omim ID
137192Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described. [provided by RefSeq
Other Designations
GABA(A) receptor beta-3 subunit|GABA-A receptor beta-3 subunit|GABA-alpha receptor beta-2 subunit|GABAA receptor beta-3 subunit
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Interactome
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Pathway
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Disease
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