GABPA (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GABPA partial ORF ( NP_002031, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQCSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVIS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GABPA
Entrez GeneID
2551GeneBank Accession#
NM_002040Protein Accession#
NP_002031Gene Name
GABPA
Gene Alias
E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A
Gene Description
GA binding protein transcription factor, alpha subunit 60kDa
Omim ID
600609Gene Ontology
HyperlinkGene Summary
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. [provided by RefSeq
Other Designations
GA binding protein transcription factor, alpha subunit|OTTHUMP00000096114|human nuclear respiratory factor-2 subunit alpha|nuclear respiratory factor 2 alpha subunit
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Interactome
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Disease
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