Products

Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

GABPA

Gene Alias

E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A

Gene Description

GA binding protein transcription factor, alpha subunit 60kDa

Omim ID

Gene Ontology

Gene Summary

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. [provided by RefSeq

Other Designations

GA binding protein transcription factor, alpha subunit|OTTHUMP00000096114|human nuclear respiratory factor-2 subunit alpha|nuclear respiratory factor 2 alpha subunit