FOSB (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human FOSB partial ORF ( NP_006723, 151 a.a. - 250 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSAPAKED
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FOSB
Entrez GeneID
2354GeneBank Accession#
NM_006732Protein Accession#
NP_006723Gene Name
FOSB
Gene Alias
AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291
Gene Description
FBJ murine osteosarcoma viral oncogene homolog B
Omim ID
164772Gene Ontology
HyperlinkGene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
activator protein 1|oncogene FOS-B
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Interactome
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