FKBP3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FKBP3 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — FKBP3
Entrez GeneID
2287GeneBank Accession#
NM_002013.2Protein Accession#
NP_002004.1Gene Name
FKBP3
Gene Alias
FKBP-25, PPIase
Gene Description
FK506 binding protein 3, 25kDa
Omim ID
186947Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq
Other Designations
FK506 binding protein 3 (25kD)|FK506-binding protein 25, T-cell|FK506-binding protein 3 (25kD)|peptidyl-prolyl cis-trans isomerase|rapamycin binding protein|rapamycin-selective 25 kDa immunophilin|rotamase
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Interactome
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Disease
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