FECH purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human FECH protein.
Immunogen
FECH (NP_000131.2, 1 a.a. ~ 423 a.a) full-length human protein.
Sequence
MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
FECH MaxPab polyclonal antibody. Western Blot analysis of FECH expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of FECH expression in transfected 293T cell line (H00002235-T02) by FECH MaxPab polyclonal antibody.
Lane 1: FECH transfected lysate(46.53 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — FECH
Entrez GeneID
2235GeneBank Accession#
NM_000140.2Protein Accession#
NP_000131.2Gene Name
FECH
Gene Alias
EPP, FCE
Gene Description
ferrochelatase (protoporphyria)
Omim ID
177000Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ferrochelatase|heme synthetase|protoheme ferro-lyase
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Interactome
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Pathway
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Disease
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