F2RL2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human F2RL2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human F2RL2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human F2RL2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — F2RL2
Entrez GeneID
2151GeneBank Accession#
F2RL2Gene Name
F2RL2
Gene Alias
PAR3
Gene Description
coagulation factor II (thrombin) receptor-like 2
Omim ID
601919Gene Ontology
HyperlinkGene Summary
Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues. [provided by RefSeq
Other Designations
Coagulation factor II receptor-like 2 (protease-actovated receptor 3)|protease-activated receptor 3|proteinase-activated receptor-3|thrombin receptor-like 2
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Pathway
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Disease
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