ESR2 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ESR2.
Immunogen
ESR2 (NP_001428, 22 a.a. ~ 121 a.a) partial recombinant protein with GST tag.
Sequence
ILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ESR2 polyclonal antibody (A01), Lot # ABNOVA060605QCS1 Western Blot analysis of ESR2 expression in MES-SA/Dx5 ( Cat # L021V1 ).ELISA
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Gene Info — ESR2
Entrez GeneID
2100GeneBank Accession#
NM_001437Protein Accession#
NP_001428Gene Name
ESR2
Gene Alias
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Gene Description
estrogen receptor 2 (ER beta)
Omim ID
601663Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq
Other Designations
estrogen receptor beta|estrogen receptor beta 4
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Interactome
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Disease
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