EIF4EBP2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human EIF4EBP2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human EIF4EBP2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human EIF4EBP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — EIF4EBP2
Entrez GeneID
1979GeneBank Accession#
EIF4EBP2Gene Name
EIF4EBP2
Gene Alias
4EBP2, PHASII
Gene Description
eukaryotic translation initiation factor 4E binding protein 2
Omim ID
602224Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq
Other Designations
OTTHUMP00000019756|phosphorylated, heat and acid stable regulated by insulin protein II
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Interactome
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Disease
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