DSC2 (Human) Matched Antibody Pair
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More Files
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Sandwich ELISA detection sensitivity ranging from approximately 27x to 3x dilution of the DSC2 293T overexpression lysate (non-denatured).
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human DSC2.
Reactivity
Human
Quality Control Testing
Standard curve using DSC2 293T overexpression lysate (non-denatured) as an analyte.
Sandwich ELISA detection sensitivity ranging from approximately 27x to 3x dilution of the DSC2 293T overexpression lysate (non-denatured).
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-DSC2 (100 ug)
2. Detection antibody: rabbit purified polyclonal anti-DSC2 (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Transfected lysate)
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Gene Info — DSC2
Entrez GeneID
1824Gene Name
DSC2
Gene Alias
ARVD11, CDHF2, DG2, DGII/III, DKFZp686I11137, DSC3
Gene Description
desmocollin 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
desmosomal glycoprotein II/III
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Interactome
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Pathway
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Disease
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