DOCK1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DOCK1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DOCK1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DOCK1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DOCK1
Entrez GeneID
1793GeneBank Accession#
DOCK1Gene Name
DOCK1
Gene Alias
DOCK180, ced5
Gene Description
dedicator of cytokinesis 1
Omim ID
601403Gene Ontology
HyperlinkGene Summary
This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis. [provided by RefSeq
Other Designations
dedicator of cyto-kinesis 1
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Interactome
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Pathway
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Disease
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