DEFA6 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DEFA6 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DEFA6
Entrez GeneID
1671GeneBank Accession#
NM_001926.2Protein Accession#
NP_001917.1Gene Name
DEFA6
Gene Alias
DEF6, HD-6
Gene Description
defensin, alpha 6, Paneth cell-specific
Omim ID
600471Gene Ontology
HyperlinkGene Summary
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq
Other Designations
defensin 6|defensin, alpha 6
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Interactome
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Disease
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