CYP4B1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CYP4B1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CYP4B1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CYP4B1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CYP4B1
Entrez GeneID
1580GeneBank Accession#
CYP4B1Gene Name
CYP4B1
Gene Alias
CYPIVB1, P-450HP
Gene Description
cytochrome P450, family 4, subfamily B, polypeptide 1
Omim ID
124075Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000009678|OTTHUMP00000009679|cytochrome P450, subfamily IVB, polypeptide 1|microsomal monooxygenase
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