CYP2C8 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CYP2C8 full-length
Host
Human
Theoretical MW (kDa)
54.01
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CYP2C8 antibody (H00001558-B01) by Western Blots.
SDS-PAGE Gel
CYP2C8 transfected lysate.
Western Blot
Lane 1: CYP2C8 transfected lysate ( 54.01 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CYP2C8
Entrez GeneID
1558GeneBank Accession#
BC020596.1Protein Accession#
AAH20596.1Gene Name
CYP2C8
Gene Alias
CPC8, MP-12/MP-20
Gene Description
cytochrome P450, family 2, subfamily C, polypeptide 8
Omim ID
601129Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq
Other Designations
OTTHUMP00000020134|P450 form 1|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8|flavoprotein-linked monooxygenase|microsomal monooxygenase|s-mephenytoin 4-hydroxylase|xenobiotic monooxygenase
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Interactome
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Pathway
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Disease
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