CLDN7 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CLDN7 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CLDN7 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CLDN7 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CLDN7
Entrez GeneID
1366GeneBank Accession#
CLDN7Gene Name
CLDN7
Gene Alias
CEPTRL2, CPETRL2, Hs.84359, claudin-1
Gene Description
claudin 7
Omim ID
609131Gene Ontology
HyperlinkGene Summary
Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells (Zheng et al., 2003 [PubMed 14502431]).[supplied by OMIM
Other Designations
Clostridium perfringens enterotoxin receptor-like 2|claudin 9
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Interactome
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Pathway
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