CHD4 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CHD4 partial ORF ( NP_001264, 1632 a.a. - 1730 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQNGETPKDLNDEKQKKNIKQRFMFNIADGGFTELHSLWQNEERAATVTKKTYEIWH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CHD4
Entrez GeneID
1108GeneBank Accession#
NM_001273Protein Accession#
NP_001264Gene Name
CHD4
Gene Alias
DKFZp686E06161, Mi-2b, Mi2-BETA
Gene Description
chromodomain helicase DNA binding protein 4
Omim ID
603277Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq
Other Designations
Mi-2 autoantigen 218 kDa protein
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Interactome
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