CENPB (Human) IP-WB Antibody Pair

Catalog # H00001059-PW1

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Size:1 Set
Price: USD $ 607.00
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Immunoprecipitation of CENPB transfected lysate using rabbit polyclonal anti-CENPB and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CENPB.

  • Specification

    Product Description

    This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (91%)

    Quality Control Testing

    Immunoprecipitation-Western Blot (IP-WB)

    Immunoprecipitation of CENPB transfected lysate using rabbit polyclonal anti-CENPB and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CENPB.

    Supplied Product

    Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-CENPB (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-CENPB (50 ug)

    Storage Instruction

    Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

  • Applications

    Immunoprecipitation-Western Blot

  • Gene Info — CENPB

    Entrez GeneID

    1059

    Gene Name

    CENPB

    Gene Alias

    -

    Gene Description

    centromere protein B, 80kDa

    Omim ID

    117140

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq

    Other Designations

    OTTHUMP00000030132|centromere autoantigen B|centromere protein B|centromere protein B (80kD)

  • Interactome
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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