CDH15 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CDH15 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CDH15 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CDH15 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CDH15
Entrez GeneID
1013GeneBank Accession#
CDH15Gene Name
CDH15
Gene Alias
CDH14, CDH3, CDHM, MCAD
Gene Description
cadherin 15, type 1, M-cadherin (myotubule)
Omim ID
114019Gene Ontology
HyperlinkGene Summary
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq
Other Designations
M-cadherin|cadherin 15|cadherin 15, M-cadherin (myotubule)|cadherin-14|cadherin-3|muscle-cadherin|myotubule-cadherin
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