CDH6 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CDH6 full-length
Host
Human
Theoretical MW (kDa)
73.9
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CDH6 antibody (H00001004-D01P) by Western Blots.
SDS-PAGE Gel
CDH6 transfected lysate.
Western Blot
Lane 1: CDH6 transfected lysate ( 73.90 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CDH6
Entrez GeneID
1004GeneBank Accession#
BC000019.2Protein Accession#
AAH00019.1Gene Name
CDH6
Gene Alias
KCAD
Gene Description
cadherin 6, type 2, K-cadherin (fetal kidney)
Omim ID
603007Gene Ontology
HyperlinkGene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [provided by RefSeq
Other Designations
K-cadherin|cadherin 6, K-cadherin (fetal kidney)|cadherin 6, type 2|cadherin, fetal kidney|kidney cadherin
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