Products

Western Blot (Transfected lysate)

Western Blot analysis of ZFP36L1 expression in transfected 293T cell line by ZFP36L1 monoclonal antibody (M02), clone 1A3.

Lane 1: ZFP36L1 transfected lysate(36.3 KDa).
Lane 2: Non-transfected lysate.

Western Blot (Recombinant protein)

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged ZFP36L1 is approximately 1ng/ml as a capture antibody.

ELISA

RNAi Knockdown (Antibody validated)

Western blot analysis of ZFP36L1 over-expressed 293 cell line, cotransfected with ZFP36L1 Validated Chimera RNAi ( Cat # H00000677-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with ZFP36L1 monoclonal antibody (M02), clone 1A3 (Cat # H00000677-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

Entrez GeneID

677

GeneBank Accession#

NM_004926

Protein Accession#

NP_004917

Gene Name

ZFP36L1

Gene Alias

BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1

Gene Description

zinc finger protein 36, C3H type-like 1

Omim ID

601064

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. [provided by RefSeq

Other Designations

EGF-response factor 1|butyrate response factor 1|early response factor Berg36|zinc finger protein, C3H type, 36-like 1