BCL3 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human BCL3 protein.
Immunogen
BCL3 (NP_005169.1, 1 a.a. ~ 446 a.a) full-length human protein.
Sequence
MDEGPVDLRTRPKAAGLPGAALPLRKRPLRAPSPEPAAPRGAAGLVVPLDPLRGGCDLPAVPGPPHGLARPEALYYPGALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLSADIAMATRADEDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVIDILRGKATRPASTSQPDPSPDRSANTSPESSSRLSSNGLLSASPSSSPSQSPPRDPPGFPMAPPNFFLPSPSPPAFLPFAGVLRGPGRPVPPSPAPGGS
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BCL3 expression in transfected 293T cell line (H00000602-T02) by BCL3 MaxPab polyclonal antibody.
Lane 1: BCL3 transfected lysate(46.8 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of BCL3 transfected lysate using anti-BCL3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with BCL3 purified MaxPab mouse polyclonal antibody (B01P) (H00000602-B01P). -
Gene Info — BCL3
Entrez GeneID
602GeneBank Accession#
NM_005178Protein Accession#
NP_005169.1Gene Name
BCL3
Gene Alias
BCL4, D19S37
Gene Description
B-cell CLL/lymphoma 3
Omim ID
109560Gene Ontology
HyperlinkGene Summary
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq
Other Designations
B-cell leukemia/lymphoma 3|B-cell lymphoma 3-encoded protein|chronic lymphatic leukemia protein
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Interactome
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Disease
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Publication Reference
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Dysregulated NF-κB signal promotes the hub gene PCLAF expression to facilitate nasopharyngeal carcinoma proliferation and metastasis.
Ma F, Zhi C, Wang M, Li T, Khan SA, Ma Z, Jing Z, Bo C, Zhou Q, Xia S, Huang S, Huang S, Zhang Z, Jia H, Cui X, Yao M, Ji T.
Biomedicine & Pharmacotherapy 2020 May; 125:109905.
Application:WB-Tr, Human, HONE1 cells.
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Dysregulated NF-κB signal promotes the hub gene PCLAF expression to facilitate nasopharyngeal carcinoma proliferation and metastasis.
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