JAG1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-JAG1 full-length
Host
Human
Theoretical MW (kDa)
133.8
Interspecies Antigen Sequence
Mouse (97); Rat (96)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-JAG1 antibody (H00000182-B01) by Western Blots.
SDS-PAGE Gel
JAG1 transfected lysate.
Western Blot
Lane 1: JAG1 transfected lysate ( 133.8 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — JAG1
Entrez GeneID
182GeneBank Accession#
NM_000214Protein Accession#
NP_000205Gene Name
JAG1
Gene Alias
AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644
Gene Description
jagged 1 (Alagille syndrome)
Gene Ontology
HyperlinkGene Summary
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq
Other Designations
OTTHUMP00000030278|jagged 1
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Interactome
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Pathway
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Disease
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