ADM DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ADM DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKRELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGYGRRRRRSLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (72)
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — ADM
Entrez GeneID
133GeneBank Accession#
NM_001124.1Protein Accession#
NP_001115.1Gene Name
ADM
Gene Alias
AM
Gene Description
adrenomedullin
Omim ID
103275Gene Ontology
HyperlinkGene Summary
Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq
Other Designations
preproadrenomedullin
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Interactome
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Pathway
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Disease
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