ADCY8 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ADCY8 partial ORF ( NP_001106, 1142 a.a. - 1251 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ADCY8
Entrez GeneID
114GeneBank Accession#
NM_001115Protein Accession#
NP_001106Gene Name
ADCY8
Gene Alias
AC8, ADCY3, HBAC1
Gene Description
adenylate cyclase 8 (brain)
Omim ID
103070Gene Ontology
HyperlinkGene Summary
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq
Other Designations
adenylate cyclase 8|adenylyl cyclase-8, brain
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Interactome
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Pathway
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Disease
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