ACCN2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ACCN2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ACCN2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ACCN2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ACCN2
Entrez GeneID
41GeneBank Accession#
ACCN2Gene Name
ACCN2
Gene Alias
ASIC, ASIC1, ASIC1A, BNaC2, hBNaC2
Gene Description
amiloride-sensitive cation channel 2, neuronal
Omim ID
602866Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Alternative splicing of this gene generates 2 transcript products. [provided by RefSeq
Other Designations
Cation channel, amiloride-sensitive, neuronal, 2|acid-sensing ion channel 1a protein
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