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- Home > Products > siRNA/Chimera > Pre-design Chimera > Signal Transduction > TACSTD2 Pre-design Chimera RNAi
TACSTD2 Pre-design Chimera RNAi
- Katalog # : H00004070-R02
- Visit Frequency :
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- Preis
- In Stock
- Verfügbarkeit
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- 10 nmol
- EUR € 165
- order now, ship in 2 weeks
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- 20 nmol
- EUR € 199
- order now, ship in 2 weeks
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- Specification
- Product Description:
- Homo sapiens tumor-associated calcium signal transducer 2 (TACSTD2), mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_002353
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 4070
- Gene Name:
- TACSTD2
- Gene Alias:
- EGP-1,GA733,GA733-1,M1S1,TROP2
- Gene Description:
- tumor-associated calcium signal transducer 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This intronless gene encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. [provided by RefSeq
- Other Designations:
- OTTHUMP00000011755,epithelial glycoprotein-1,membrane component, chromosome 1, surface marker 1 (40kD glycoprotein, identified by monoclonal antibody GA733)
