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KRAS monoclonal antibody (M02), clone 4F3
Katalog # : H00003845-M02
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100 ug
EUR € 299
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Product Description: Mouse monoclonal antibody raised against a partial recombinant KRAS.
Immunogen: KRAS (NP_004976, 16 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence: KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTV
Quality Control Testing: Antibody Reactive Against Recombinant Protein.
Storage Buffer: In 1x PBS, pH 7.2
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Western Blot (Cell lysate) KRAS monoclonal antibody (M02), clone 4F3 Western Blot analysis of KRAS expression in HeLa ( Cat # L013V1 ).
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Western Blot (Transfected lysate) Western Blot analysis of KRAS expression in transfected 293T cell line by KRAS monoclonal antibody (M02), clone 4F3.
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Sandwich ELISA (Recombinant protein) Detection limit for recombinant GST tagged KRAS is approximately 0.3ng/ml as a capture antibody.
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Western Blot (Transfected lysate)
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Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
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Gene Alias: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2
Gene Description: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Gene Summary: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq
Other Designations: K-ras p21 protein,Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog,PR310 c-K-ras oncogene,c-K-ras2 protein,c-Kirsten-ras protein,cellular c-Ki-ras2 proto-oncogene,oncogene KRAS2,transforming protein p21,v-Ki-ras2 Kirsten rat sarcoma 2 viral oncoge
Abnormalities, Multiple Acute Disease Adenocarcinoma Adenocarcinoma, Bronchiolo-Alveolar Adenocarcinoma, Mucinous Adenocarcinoma, Papillary Adenoma Adenomatous Polyposis Coli Alcoholism Anus Neoplasms Biliary Tract Neoplasms Breast cancer Breast Neoplasms Carcinoma Carcinoma, Adenosquamous Carcinoma, Endometrioid Carcinoma, Giant Cell Carcinoma, Large Cell Carcinoma, Medullary
Carcinoma, Non-Small-Cell Lung Carcinoma, Pancreatic Ductal Carcinoma, Papillary Carcinoma, Papillary, Follicular Carcinoma, Renal Cell Carcinoma, Squamous Cell Carcinoma, Transitional Cell Cardiomyopathy, Hypertrophic Cell Transformation, Neoplastic Cholangiocarcinoma Chromosomal Instability Chromosome Aberrations Chromosome Deletion Cognition Disorders Colitis, Ulcerative Colon cancer Colonic Neoplasms Colonic Polyps Colorectal Neoplasms Colorectal Neoplasms, Hereditary Nonpolyposis Common Bile Duct Neoplasms Crohn Disease Crohn's disease Cystadenocarcinoma, Mucinous Cystadenocarcinoma, Serous Developmental Disabilities Diarrhea Dilatation, Pathologic Disease Progression Down Syndrome Drug Toxicity Endometrial Hyperplasia Endometrial Neoplasms Endometriosis Eosinophilia Esophageal Neoplasms Exanthema Gastrointestinal Stromal Tumors Genetic Predisposition to Disease Genomic Instability Glioma Head and Neck Neoplasms Heart Defects, Congenital HIV Infections Hyperplasia Immunologic Deficiency Syndromes Inflammation Inflammatory Bowel Diseases Kidney Failure, Chronic Kidney Neoplasms LEOPARD Syndrome Leukemia Leukemia, B-Cell, Acute Leukemia, Lymphocytic, Acute, L1 Leukemia, Myelocytic, Acute Leukemia, Myeloid Leukemia, Myeloid, Acute Leukemia, Myelomonocytic, Chronic Leukemia, Myelomonocytic, Juvenile Liver Neoplasms Lung Neoplasms Lymphatic Metastasis Lymphoma, Non-Hodgkin Meningeal Neoplasms Meningioma Microsatellite Instability Mouth Neoplasms Multiple Myeloma Myoma Nausea Necrosis Neoplasm Invasiveness Neoplasm Metastasis Neoplasm Recurrence, Local Neoplasms Neoplasms, Basal Cell Neoplasms, Germ Cell and Embryonal Neoplasms, Glandular and Epithelial Neoplasms, Multiple Primary Neoplasms, Radiation-Induced Neoplasms, Second Primary Neoplasms, Squamous Cell Nerve Sheath Neoplasms Neurofibromatosis Neurofibromatosis 1 Neutropenia Noonan Syndrome Obesity Obesity Ovarian cancer Ovarian Failure, Premature Ovarian Neoplasms Pancreatic cancer Pancreatic Neoplasms Pancreatitis, Chronic Papillomavirus Infections Paraproteinemias Peritoneal Neoplasms Polycystic Ovary Syndrome Precancerous Conditions Prostatic Neoplasms Puberty, Delayed Puberty, Precocious Pulmonary Disease, Chronic Obstructive Pulmonary Valve Stenosis Ras oncogene Rectal Neoplasms Recurrence Retinal Neoplasms Retinoblastoma Retinoblastoma Sarcoma Skin Abnormalities Stomach Neoplasms Syndrome Testicular Neoplasms Thrombophilia Thyroid Diseases Thyroid Neoplasms Tobacco Use Disorder Tonsillar Neoplasms Urinary Bladder Neoplasms Uterine Neoplasms Werner syndrome
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