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- Home > Products > Polyclonal Ab > Phospho-Specific > ILK (phospho S246) polyclonal antibody
ILK (phospho S246) polyclonal antibody
- Katalog # : PAB3063
- Visit Frequency :
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- Preis
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- Verfügbarkeit
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- 100 ug
- EUR € 305
- order now, ship in 5 days
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Email : sales@abnova.com
Phone : +49-6221-825877
Fax : +49-2381-9994411- Produkte werden direkt an den Kunden versandt.
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ILK.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S246 of human ILK1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis.
Li Y, Yang J, Dai C, Wu C, Liu Y.J Clin Invest. 2003 Aug;112(4):503-16.
- 2.
- Characterisation of integrin-linked kinase signalling in sporadic human colon cancer.
Marotta A, Parhar K, Owen D, Dedhar S, Salh B.Br J Cancer. 2003 Jun 2;88(11):1755-62.
- 3.
- Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation.
Troussard AA, Mawji NM, Ong C, Mui A, St -Arnaud R, Dedhar S.J Biol Chem. 2003 Jun 20;278(25):22374-8. Epub 2003 Apr 8.
- Application Image
- Western Blot
- Immunohistochemistry
- ELISA
- Entrez GeneID:
- 3611
- Protein Accession#:
- Q13418;NP_004508
- Gene Name:
- ILK
- Gene Alias:
- DKFZp686F1765,P59
- Gene Description:
- integrin-linked kinase
- Omim ID:
- 602366
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- -
