Store at -20°C on dry atmosphere. After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Applications
Western Blot (Cell lysate)
Western blot analysis of whole cell extracts with HDAC1 polyclonal antibody (Cat # PAB19089). Lane 1 : MM453. Lane 2 : MCF-7. Lane 3 : HeLa. Lane 4 : SMMC.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq