Rabbit polyclonal antibody raised against synthetic peptide of CYR61.
Immunogen:
A synthetic peptide corresponding to amino acids 150-250 of human CYR61.
Host:
Rabbit
Reactivity:
Human
Specificity:
This antibody is specific to CYR61 protein.
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (1:200) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (0.09% sodium azide)
Storage Instruction:
Store at 4°C. Do not freeze.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Western blot analysis of cleaved CYR61 in MDA-MB-231 cell lysate using CYR61 polyclonal antibody (Cat # PAB12525). Photo courtesy of Dr. Lupu's Lab, Northwestern University. Image by Dr. Ingrid Espinoza.
Staining of CYR61 on human endometrium using CYR61 polyclonal antibody (Cat # PAB12525). Photo courtesy of Dr. rer. nat. Isabella Gashaw, University Duisburg-Essen.
CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and augments growth factor-induced DNA synthesis in the same cell type.[supplied by OMIM
Other Designations:
OTTHUMP00000012303,cysteine-rich heparin-binding protein 61,cysteine-rich, anigogenic inducer, 61
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