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APOE (Human) Native Protein
Katalog # : P4281
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50 ug
EUR € 419
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Product Description: Human APOE native protein from human plasma.
Preparation Method:
Native protein purified from human plasma
Purity: ≥ 95% by SDS-PAGE
Storage Buffer: In 50 mM NH4 HCO3 , pH 8.0
Storage Instruction: Store at -80°C.
Gene Alias: AD2,LPG,MGC1571,apoprotein
Gene Description: apolipoprotein E
Gene Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
Other Designations: apolipoprotein E3
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