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PDGFRB (Human) Recombinant Protein   BioActive

  • Katalog # : P4248
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  • 5 ug
  • EUR € 279
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    Phone : +49-6221-825877
    Fax : +49-2381-9994411
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  • Specification
  • Product Description:
  • Human PDGFRB (NP_002600.1, 557 a.a. - end) partial recombinant protein expressed in Sf9 cells.
  • Theoretical MW (kDa):
  • 96
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • ≥ 90% by SDS-PAGE
  • Activity:
  • The specific activity of PDGFRb was determined to be 20 nmol/min/mg as per activity assay protocol.
  • Quality Control Testing:
  • SDS-PAGE Result

    QC Testing of P4248
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 5159
  • Gene Name:
  • PDGFRB
  • Gene Alias:
  • CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1
  • Gene Description:
  • platelet-derived growth factor receptor, beta polypeptide
  • Gene Summary:
  • This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
  • Other Designations:
  • beta platelet-derived growth factor receptor,platelet-derived growth factor receptor beta,soluble PDGFRb variant 1
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