Human CASP9 (P55211) recombinant protein expressed in Escherichia coli.
Form:
Lyophilized
Preparation Method:
Escherichia coli expression system
Purity:
≥ 90% by SDS-PAGE
Activity:
> 400 units/mg
Storage Buffer:
No additive
Storage Instruction:
Store at -80°C on dry atmosphere. After reconstitution with PBS containing 15% glycerol 1 uL per unit, store at -80°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq
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