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IL2 (Human) Recombinant Protein
Katalog # : P3633
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50 ug
EUR € 229
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Product Description: Human IL2 (P60568, 21 a.a. - 153 a.a.) partial recombinant protein expressed in Escherichia coli .
Sequence: APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
Preparation Method:
Escherichia coli expression system
Purification: Ion exchange column and HPLC reverse phase column
Purity: > 97% by SDS-PAGE and HPLC
Endotoxin Level: < 0.1 ng/ug (1 EU/ug)
Activity: The ED50 was determined by the dose dependent proliferation of murine BALB/c 3T3 cells (measured by3H-thymidine uptake), and was found to be less than 0.1 ng/mL. , corresponding to a specific activity of >1.0 x 107 units/mg.
Storage Buffer: Lyophilized from PBS, pH 7.2
Storage Instruction: Store at -20°C on dry atmosphere for 2 years.
Gene Alias: IL-2,TCGF,lymphokine
Gene Description: interleukin 2
Gene Summary: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq
Other Designations: T cell growth factor,aldesleukin,interleukin-2,involved in regulation of T-cell clonal expansion
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