The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤0.1 ng/mL, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Storage Buffer:
Lyophilized from PBS, pH 7.0
Storage Instruction:
Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq