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AKT1 (phospho S124) Peptide   

  • Katalog # : P1266
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  • 100 ug
  • EUR € 129
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  • Specification
  • Product Description:
  • This synthetic peptide is phosphorlated on S124 of human AKT1 and is used as the immunogen for PAB0402.
  • Sequence:
  • Amino acid near S124 of Human AKT1
  • Form:
  • Lyophilized with 100% acetonitrile
  • Storage Buffer:
  • Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at-20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product is for research use only. Not for use in diagnostics or therapeutics.
  • Applications
  • Blocking
  • Application Image
  • Blocking
  • Gene Information
  • Entrez GeneID:
  • 207
  • Protein Accession#:
  • NP_005154;P31749
  • Gene Name:
  • AKT1
  • Gene Alias:
  • AKT,MGC99656,PKB,PKB-ALPHA,PRKBA,RAC,RAC-ALPHA
  • Gene Description:
  • v-akt murine thymoma viral oncogene homolog 1
  • Gene Summary:
  • The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
  • Other Designations:
  • RAC-alpha serine/threonine-protein kinase,murine thymoma viral (v-akt) oncogene homolog-1,protein kinase B,rac protein kinase alpha
  • Interactome
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