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IL1B monoclonal antibody, clone 2H12
Katalog # : MAB9933
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100 ug
EUR € 289
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Product Description: Mouse monoclonal antibody raised against partial recombinant IL1B.
Immunogen: Recombinant protein corresponding to amino acids 118-269 of human IL1B.
Purification: Affinity purification
Recommend Usage: Western blot (1:1000)
Storage Buffer: In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction: Store at 4°C. For long term storage store at -20°C.
Western Blot (Cell lysate)
Western Blot (Recombinant protein) Western blot analysis of recombinant IL1B protein with IL1B monoclonal antibody, clone 2H12 (Cat # MAB9933) at 1:1000 dilution.
Immunohistochemistry Immunohistochemical staining of human liver cancer tissue section with IL1B monoclonal antibody, clone 2H12 (Cat # MAB9933) at 1:10 dilution.
Western Blot (Cell lysate)
Western Blot (Recombinant protein)
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Gene Alias: IL-1,IL1-BETA,IL1F2
Gene Description: interleukin 1, beta
Gene Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
Other Designations: catabolin,preinterleukin 1 beta,pro-interleukin-1-beta
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