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ESR1 monoclonal antibody, clone 5D4B1,5D4E3
Katalog # : MAB8304
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100 uL
EUR € 289
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Product Description: Mouse monoclonal antibody raised against partial recombinant ESR1.
Immunogen: Recombinant protein corresponding to truncated human ESR1.
Recommend Usage: Western Blot (1:500-1:2000)
Storage Buffer: In ascites
Storage Instruction: Store at -20°C.
Western Blot Western blot analysis using ESR1 monoclonal antibody, clone 5D4B1, 5D4E3 (Cat # MAB8304) against truncated ESR1 recombinant protein (Lane 1) and MCF-7 cell lysate (Lane 2).
Gene Alias: DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1
Gene Description: estrogen receptor 1
Gene Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq
Other Designations: OTTHUMP00000017718,OTTHUMP00000017719,estrogen receptor alpha
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