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- Home > Products > Monoclonal Ab > Mouse > Bcl2l11 monoclonal antibody, clone Ham151-149
Bcl2l11 monoclonal antibody, clone Ham151-149
- Katalog # : MAB7553
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- 100 ug
- EUR € 305
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- Specification
- Product Description:
- Hamster monoclonal antibody raised against native Bcl2l11.
- Immunogen:
- Native purified Bcl2l11 from mouse BimL (w/o transmembrane region) and Bcl-xL (w/o transmembrane region)-6xHis tag, purified from Hi5 cells.
- Host:
- Hamster
- Theoretical MW (kDa):
- 19-24
- Reactivity:
- Mouse
- Specificity:
- This antibody reacts with mouse Bim, a 19-24 KDa pro-apoptotic protein (Bcl-2 family) which regulates immunological responses.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Recommend Usage:
- Western Blot (1-2 mg/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis.
Wang X, Xing D, Liu L, Chen WR.FEBS Lett. 2009 Jun 18;583(12):1873-9. Epub 2009 May 8.
- 2.
- Bim and Bcl-2 mutually affect the expression of the other in T cells.
Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P.J Immunol. 2007 Sep 15;179(6):3417-24.
- 3.
- Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7.
Oliver PM, Wang M, Zhu Y, White J, Kappler J, Marrack P.J Exp Med. 2004 Nov 1;200(9):1179-87.
- Application Image
- Western Blot
- Immunocytochemistry
- Immunoprecipitation
- Flow Cytometry
- Entrez GeneID:
- 12125
- Gene Name:
- Bcl2l11
- Gene Alias:
- 1500006F24Rik,Bim,Bod
- Gene Description:
- BCL2-like 11 (apoptosis facilitator)
- Gene Ontology:
- Hyperlink
- Other Designations:
- BCL2-like 11 apoptosis facilitator,Bcl2 interacting mediator of cell death,OTTMUSP00000016362,OTTMUSP00000016364,OTTMUSP00000016365
