Rabbit monoclonal antibody raised against synthetic peptide of EGFR.
Immunogen:
A synthetic peptide corresponding to C-terminus of human EGFR.
Host:
Rabbit
Theoretical MW (kDa):
185
Reactivity:
Human
Form:
Liquid
Purification:
Affinity purification
Recommend Usage:
Western Blot (1:25) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM PBS, pH 7.4 (BSA, sodium azide)
Storage Instruction:
Store at 4°C. Do not freeze.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Applications
Western Blot (Cell lysate)
Western blot analysis of A-431 cell lysate with EGFR monoclonal antibody, clone SP84 (Cat # MAB10038).
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
Other Designations:
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor
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