Mouse monoclonal antibody raised against native AFP.
Immunogen:
Native purified human AFP.
Host:
Mouse
Reactivity:
Human
Specificity:
This antibody is specific to human AFP. Cross-reactivity to other species or similar molecules have not been investigated. Epitope different from MAB0193, MAB0194, MAB0196, MAB0197
Form:
Liquid
Isotype:
IgG1
Recommend Usage:
The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM phosphate buffer, 500 mM NaCl, pH 7.4 (15 mM sodium azide)
Storage Instruction:
Store in the dark at 4°C. Avoid prolonged exposure to light.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq