Transient overexpression cell lysate was tested with Anti-DKK1antibody (H00022943-D01P)byWesternBlots. SDS-PAGE Gel DKK1 transfected lysate. Western Blot Lane 1: DKK1 transfected lysate ( 28.7 KDa) Lane 2: Non-transfected lysate.
Storage Buffer:
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction:
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq
Other Designations:
OTTHUMP00000019617,dickkopf homolog 1,dickkopf related protein-1,dickkopf-1 like