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ABCG2 purified MaxPab rabbit polyclonal antibody (D01P)
Katalog # : H00009429-D01P
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100 ug
EUR € 289
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Product Description: Rabbit polyclonal antibody raised against a full-length human ABCG2 protein.
Immunogen: ABCG2 (AAH21281.1, 1 a.a. ~ 655 a.a) full-length human protein.
Sequence: MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS
Quality Control Testing: Antibody reactive against mammalian transfected lysate.
Storage Buffer: In 1x PBS, pH 7.2
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Western Blot (Transfected lysate) Western Blot analysis of ABCG2 expression in transfected 293T cell line (H00009429-T01 ) by ABCG2 MaxPab polyclonal antibody.
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Western Blot (Transfected lysate)
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Gene Alias: ABC15,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,EST157481,MGC102821,MRX,MXR,MXR1
Gene Description: ATP-binding cassette, sub-family G (WHITE), member 2
Gene Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq
Other Designations: ABC transporter,ATP-binding cassette transporter G2,ATP-binding cassette, sub-family G, member 2,breast cancer resistance protein,mitoxantrone resistance protein,placenta specific MDR protein
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