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PTPRN2 MaxPab mouse polyclonal antibody (B01)
Katalog # : H00005799-B01
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Product Description:
Mouse polyclonal antibody raised against a full-length human PTPRN2 protein.
Immunogen:
PTPRN2 (NP_570858, 1 a.a. ~ 986 a.a) full-length human protein.
Sequence:
MGPPLPLLLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGPRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQPSEEEARGYIVTDREVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ
Quality Control Testing:
Antibody reactive against mammalian transfected lysate.
Storage Buffer:
No additive
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
Western Blot (Tissue lysate)
PTPRN2 MaxPab polyclonal antibody. Western Blot analysis of PTPRN2 expression in human kidney.
Protocol Download
Western Blot (Transfected lysate)
Western Blot analysis of PTPRN2 expression in transfected 293T cell line (H00005799-T01 ) by PTPRN2 MaxPab polyclonal antibody. Lane 1: PTPRN2 transfected lysate(108.46 KDa). Lane 2: Non-transfected lysate.
Protocol Download
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Immunoperoxidase of purified MaxPab antibody to PTPRN2 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
Protocol Download
Western Blot (Tissue lysate)
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Western Blot (Transfected lysate)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Alias:
IA-2beta,IAR,ICAAR,PTPRP
Gene Description:
protein tyrosine phosphatase, receptor type, N polypeptide 2
Gene Summary:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
Other Designations:
IAR/receptor-like protein-tyrosine phosphatase,phogrin,protein tyrosine phosphatase receptor pi,tyrosine phosphatase IA-2 beta