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- Home > Products > siRNA/Chimera > Pre-design Chimera > Plasma/Serum > ITGA4 Pre-design Chimera RNAi
ITGA4 Pre-design Chimera RNAi
- Katalog # : H00003676-R01
- Visit Frequency :
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- 10 nmol
- EUR € 165
- order now, ship in 2 weeks
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- 20 nmol
- EUR € 199
- order now, ship in 2 weeks
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- Specification
- Product Description:
- Homo sapiens integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4), mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000885
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 3676
- Gene Name:
- ITGA4
- Gene Alias:
- CD49D,IA4,MGC90518
- Gene Description:
- integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
- Omim ID:
- 192975
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. [provided by RefSeq
- Other Designations:
- 269C wild type,antigen CD49D, alpha-4 subunit of VLA-4 receptor,integrin alpha 4,integrin alpha-4 subunit,very late activation protein 4 receptor, alpha 4 subunit
