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F7 MaxPab mouse polyclonal antibody (B01)
Katalog # : H00002155-B01
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50 uL
EUR € 299
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Product Description: Mouse polyclonal antibody raised against a full-length human F7 protein.
Immunogen: F7 (NP_062562.1, 1 a.a. ~ 444 a.a) full-length human protein.
Sequence: MVSQALRLLCLLLGLQGCLAAVFVTQEEAHGVLHRRRRANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
Quality Control Testing: Antibody reactive against mammalian transfected lysate.
Storage Buffer: No additive
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note: For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
Western Blot (Transfected lysate) Western Blot analysis of F7 expression in transfected 293T cell line (H00002155-T01 ) by F7 MaxPab polyclonal antibody.
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Western Blot (Transfected lysate)
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Gene Description: coagulation factor VII (serum prothrombin conversion accelerator)
Gene Summary: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq
Other Designations: FVII coagulation protein,OTTHUMP00000018733,OTTHUMP00000018734,coagulation factor VII,eptacog alfa
Abortion, Habitual Activated Protein C Resistance Acute Disease Alzheimer Disease Alzheimer disease Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis Anemia, Sickle Cell Anemia, sickle cell Angina Pectoris Angina, Unstable Arterial Occlusive Diseases Arteriosclerosis Atherosclerosis Atherosclerosis Atrial Fibrillation Birth Weight Blood Coagulation Disorders Body Weight
Brain Ischemia Bronchopulmonary Dysplasia Budd-Chiari Syndrome Carcinoma, Hepatocellular Cardiovascular Diseases Carotid Artery Diseases Carotid Stenosis Cerebral Hemorrhage Cerebral Infarction Cerebral Palsy Cerebrovascular Accident Cerebrovascular Disorders Chorioamnionitis Chronic Disease Connective Tissue Diseases Constriction, Pathologic Coronary Artery Disease Coronary Disease Coronary Restenosis Coronary Stenosis Coronary Thrombosis Diabetes Complications Diabetes Mellitus Diabetes Mellitus, Type 2 Diabetic Angiopathies Disease Progression Edema Factor VII Deficiency Factor XIII Deficiency Fetal Diseases Fetal Membranes, Premature Rupture Genetic Diseases, Inborn Genetic Predisposition to Disease Heart Defects, Congenital Hemophilia A Hemorrhage Hemorrhagic Disease of Newborn Hemorrhagic Disorders Hepatitis, Chronic Hypercholesterolemia Hyperlipidemias Hyperlipoproteinemia Type II Hypertension Infant, Premature, Diseases Infection Inflammation Insulin Resistance Intracranial Embolism Intracranial Thrombosis Ischemic Attack, Transient Kidney Failure, Chronic Leukomalacia, Periventricular Liver Cirrhosis Metabolic Syndrome X Migraine Disorders Musculoskeletal Diseases Myocardial Infarction Myocardial Ischemia Neoplasms Obesity Obesity Obstetric Labor, Premature Osteoporosis Periodontitis Peripheral Vascular Diseases Pre-Eclampsia Pregnancy Complications, Hematologic Premature Birth Recurrence Sepsis Skin Diseases Stroke Subarachnoid Hemorrhage Thromboembolism Thrombophilia Thrombosis Venous Thrombosis Vitamin K Deficiency Werner syndrome
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