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- Home > Products > siRNA/Chimera > Pre-design Chimera > Enzyme > Kinase > AKT2 Pre-design Chimera RNAi
AKT2 Pre-design Chimera RNAi
- Katalog # : H00000208-R02
- Visit Frequency :
- Größe
- Preis
- In Stock
- Verfügbarkeit
- Cart
- 10 nmol
- EUR € 165
- order now, ship in 2 weeks
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- 20 nmol
- EUR € 199
- order now, ship in 2 weeks
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Phone : +49-6221-825877
Fax : +49-2381-9994411- Produkte werden direkt an den Kunden versandt.
- Specification
- Product Description:
- Homo sapiens v-akt murine thymoma viral oncogene homolog 2 (AKT2), mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001626
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 208
- Gene Name:
- AKT2
- Gene Alias:
- PKBB,PKBBETA,PRKBB,RAC-BETA
- Gene Description:
- v-akt murine thymoma viral oncogene homolog 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq
- Other Designations:
- Murine thymoma viral (v-akt) homolog-2,rac protein kinase beta
- Gene Pathway
- Acute myeloid leukemia
- Adipocytokine signaling pathway
- Apoptosis
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Glioma
- Insulin signaling pathway
- Jak-STAT signaling pathway
- MAPK signaling pathway
- Melanoma
- mTOR signaling pathway
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prostate cancer
- Renal cell carcinoma
- Small cell lung cancer
- T cell receptor signaling pathway
- Tight junction
- Toll-like receptor signaling pathway
- VEGF signaling pathway
- Related Disease
- Adenocarcinoma
- Adenocarcinoma, Papillary
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Drug Toxicity
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- HIV Infections
- Hypercholesterolemia
- Insulin Resistance
- Lipodystrophy
- Lung Neoplasms
- Metabolic Syndrome X
- Neoplasms, Glandular and Epithelial
- Ovarian cancer
- Ovarian Neoplasms
