Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
Quality Control Testing:
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product:
DAPI Counterstain (1500 ng/mL ) 250 uL
Storage Instruction:
Store at 4°C in the dark.
Note:
Hybridization position of the probes on the chromosome:
Probe 1: Size: Fluorophore: Location:
MYB(Texas Red) Approximately 500kb Texas Red 6q22-23
Probe 2: Size: Fluorophore: Location:
MYB(FITC) Approximately 780kb FITC 6q22-23
Probe Gap:
The length of overlap between two probes is approximately 20 kb.
Origin:
Human
Source:
Genomic DNA
Notice:
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq