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KDR (Human) Recombinant Protein
Katalog # : P4793
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100 ug
EUR € 855
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Product Description: Human KDR (NM_002253, 807 a.a. - 1356 a.a.) partial recombinanat protein with GST tag expressed in Sf9 cells.
Theoretical MW (kDa): 87.095
Preparation Method:
Insect cell (Sf9) expression system
Purification: GST-Affinity Chromatography
Concentration: 0.072 ug/uL
Activity: 218 pmol/ug x min
Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer: In 50 mM Hepes, 100 mM NaCl, pH 7.5 (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Storage Instruction: Store at -80°C.
Note: Result of activity analysis
Gene Alias: CD309,FLK1,VEGFR,VEGFR2
Gene Description: kinase insert domain receptor (a type III receptor tyrosine kinase)
Gene Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq
Other Designations: soluble VEGFR2,vascular endothelial growth factor receptor 2
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