This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq
Other Designations:
DNA repair exonuclease REC1,OTTHUMP00000115992,RAD1 homolog,Rad1-like DNA damage checkpoint,cell cycle checkpoint protein Hrad1,checkpoint control protein HRAD1,exonuclease homolog RAD1
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